Necrosulfonamide,IC-01211680
Necrosulfonamide is a necroptosis inhibitor acting by selectively targeting the mixed lineage kinase domain-like protein (MLKL). Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a critical substrate of RIP3 during the induction of necrosis[1].
[1]. Sun L, et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell. 2012;148(1-2):213-227.
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Order Information |
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Cat./REF. |
Size |
Price($£© |
Price(€) |
Price(£¤/CNY£© |
Price(£¤/JYP£© |
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IC-01211680 |
5mg |
$75.50 |
€ 90.60 |
£¤755.00 |
£¤15,024.50 |
|
IC-01211680 |
25mg |
$302.00 |
€ 362.40 |
£¤3,020.00 |
£¤60,098.00 |
|
IC-01211680 |
100mg |
$906.00 |
€ 1,087.20 |
£¤9,060.00 |
£¤180,294.00 |
