Taurine , 107-35-7

Cat.No.:IC-0131026

Product Information

Biological Activity

Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

Species

Mouse

Rat

Rabbit

Guinea pig

Hamster

Dog

Weight (kg)

0.02

0.15

1.8

0.4

0.08

10

Body Surface Area (m2)

0.007

0.025

0.15

0.05

0.02

0.5

Km factor

3

6

12

8

5

20

Animal A (mg/kg) = Animal B (mg/kg) multiplied by  (Animal B Km / Animal A Km)
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Order Information

Quantity

Price($)

Price(€)

Price(£¤/CNY)

1g

$50.00

€60.00

£¤500.00

5g

$80.00

€96.00

£¤800.00

25g

$150.00

€180.00

£¤1,500.00

Free Delivery on orders over $350.00.

Chemical Information

Molecular Weight

125.15

Formula

C2H7NO3S

CAS Number

 107-35-7

Purity

>99.00%

Solubility

DMSO£º1 mg/mL £¬Water£º25 mg/mL .

Storage

2-8¡æ

Reference

[1]. Ripps H, Shen W. Review: taurine: a "very essential" amino acid. Mol Vis. 2012;18:2673-2686.  [Content Brief]
[2]. Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65.  [Content Brief]
[3]. Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50(5):527-535.  [Content Brief]

We Devoted Ourselves To The Development Of Biomedical Research Reagent.