Product Information

Biological Activity

L-Ascorbic Acid£¨Vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

Species

Mouse

Rat

Rabbit

Guinea pig

Hamster

Dog

Weight (kg)

0.02

0.15

1.8

0.4

0.08

10

Body Surface Area (m2)

0.007

0.025

0.15

0.05

0.02

0.5

Km factor

3

6

12

8

5

20

Animal A (mg/kg) = Animal B (mg/kg) multiplied by  (Animal B Km / Animal A Km)
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Order Information

Quantity

Price($)

Price($)

Availability

500mg

$120.00

€144.00

In stock

1g

$192.00

€230.40

In stock

5g

$720.00

€864.00

In stock

Free Delivery on orders over $350.00.

Chemical Information

Molecular Weight

176.12

Formula

C6H8O6

CAS Number

50-81-7

Purity

¡Ý98.00%

Solubility

35mg/mL in DMSO (198.73mM), 35mg/mL in Water(198.73mM)

Storage

4¡ãC, protect from light

Reference

[1].Michael T Nelson, et al. J Neurosci. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate

[2].Sebastian J Padayatty, et al. J Am Coll Nutr. Vitamin C as an antioxidant: evaluation of its role in disease prevention.

We Devoted Ourselves To The Development Of Biomedical Research Reagent.