Methacholine chloride£¬IC-0155651
Product Information
Biological Activity
Methacholine chloride is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system.
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species
Mouse
Rat
Rabbit
Guinea pig
Hamster
Dog
Weight (kg)
0.02
0.15
1.8
0.4
0.08
10
Body Surface Area (m2)
0.007
0.025
0.15
0.05
0.02
0.5
Km factor
3
6
12
8
5
20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by (Animal B Km / Animal A Km)
Order Information
Quantity
Price($)
Price($)
Availability
50mg
$99.00
€108.90
In stock
200mg
$199.00
€218.90
In stock
500mg
$399.00
€438.90
In stock
Free Delivery on orders over $350.00.
Chemical Information
Molecular Weight
195.69
Formula
C8H18ClNO2
CAS Number
62-51-1
Purity
>98%
Solubility
DMSO : ¡Ý 42 mg/mL (214.63 mM)
Storage
Store at -20¡ãC, stored under nitrogen
Reference
[1]. Birnbaum S, et al. Methacholine challenge testing: identifying its diagnostic role, testing, coding, and reimbursement. Chest. 2007 Jun;131(6):1932-5.
We Devoted Ourselves To The Development Of Biomedical Research Reagent.
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
